Baby Cos lettuce is best suited for both raw and cooked applications such as braising and lightly boiling. The leaves can be used fresh and torn for salads, or they can be used as a dipping vessel for sauces, dips, and fillings. They can also be layered on sandwiches, burgers, and in wraps for added crunch or used as mini shells for tacos. In addition to fresh preparations, baby cos lettuce can withstand high heat which makes it suitable for grilling, braising with cooked vegetables and meat, adding to soups, and chopping and mixing into stir-fries.

To store, Baby Cos Lettuce is best wrapped in paper towels to absorb excess moisture in the crisper drawer of the refrigerator.